Key takeaways
- O'Fallon, Illinois is in St. Clair County on I-64, east of Fairview Heights. The clinic has no room there.
- O'Fallon, Missouri is in St. Charles County on I-70, west of the Missouri River. The clinic's room is at 2163 West Terra Lane there.
- For almost everyone on the east bank, Hazelwood or Tesson Ferry is the shorter and better choice.
- The O'Fallon, Missouri room runs a different schedule: Monday, Tuesday, Thursday 9 to 6, Wednesday and Friday by appointment, closed 12 to 2.
O'Fallon, Illinois
St. Clair County. I-64, east of Fairview Heights and Swansea, west of Shiloh and Scott Air Force Base. A growing town with a downtown along State Street, a lot of new subdivisions, and a commute that runs west on 64 to the Poplar Street Bridge. If you live there, the clinic's rooms are across the river like everyone else's on this side, and the nearest ones are Tesson Ferry by I-55 south or Hazelwood by I-70 north, depending on which end of St. Louis County you know better.
The clinic has no room in O'Fallon, Illinois. This guide would say so in larger type if it could.

O'Fallon, Missouri
St. Charles County. I-70, west of the Missouri River, between St. Peters and Wentzville. A large suburb that keeps growing out along the interstate. Missouri Injury Clinic's third room is here, listed on its site under the Lake St. Louis name, at 2163 West Terra Lane, O'Fallon, MO 63366, phone (636) 280-0990.
The hours are different from the other two rooms and worth noting before you drive: Monday, Tuesday, and Thursday 9 to 6, Wednesday and Friday by appointment, closed from 12 to 2 daily like the others. A Wednesday crossing without a call first is a long drive to a door that may not open.
Who should actually drive there from the Metro East
Almost nobody, and the guide says that without apology. From Collinsville, the trip is 55/70 to the Stan Musial, I-70 west through the city, past the airport, across the Missouri River on the Blanchette Bridge, and on through St. Charles and St. Peters. It is the longest drive of the three by a wide margin. It makes sense in exactly one case: your week already runs that direction. You work in Wentzville, you have family in St. Peters, you are out there three days a week anyway. Then the O'Fallon, Missouri room is a reasonable place to be examined, and the room's own page has the particulars.
Everyone else
Hazelwood or Tesson Ferry. The rooms page sorts every Metro East town to one or the other, and bridge by bridge explains why. The short version: the northern and downtown crossings point at Hazelwood at (314) 627-1411; the Jefferson Barracks Bridge points at Tesson Ferry at (314) 530-5480. Both keep Monday to Thursday 9 to 6 and Friday 9 to 12, closed 12 to 2.
Other doubled names, while we are here
Columbia, Illinois is the Monroe County town on Route 3 and I-255, not the college town in the middle of Missouri. Troy, Illinois is on 55/70 in Madison County; there is also a Troy in Lincoln County, Missouri, up Highway 61. Madison is both a county on the Illinois side and a small city inside it on Route 3. Granite City is one place, and grateful for it.
None of this would matter except that people type a town name into a search box while their neck hurts and end up on the wrong side of the wrong river. The desk's entire job is to keep that from happening. If a claim is ever part of your story, the dated record from the first exam is what everyone will ask for, and it reads the same from any of the three rooms; the only thing the geography changes is how long you are in the car.
Chest pain, a sudden severe headache, weakness or numbness on one side, trouble speaking, a loss of bowel or bladder control, or a head injury with vomiting or worsening confusion is an emergency room trip right now, not a call to a clinic. Educational only. Nothing on this page is medical advice or a diagnosis; the person to ask is a licensed clinician who has examined you. Facts about the clinic come from moinjuryclinic.com. Emergency symptoms go to an emergency room, on whichever side of the river you are standing, not to a clinic or a website.